Paul Hontz nails it.

As I listened to Steve speak, one phrase kept gnawing at me. Steve said that the iPad was “a post-pc device”. As an iOS developer who makes his living building apps for iPads and iPhones, I disagree. You see iOS has this ball and chain attached to it called “iTunes” that runs on a typical PC. The first time you turn your iPad on you’re greeted with this screen on the right prompting you to plug your iPad into a computer so it can be setup. You can’t even turn your iPad on the first time without being tethered to iTunes.

Yep.